The Drosophila Model in Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Deng, Wu-Min (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Advances in Experimental Medicine and Biology, 1167
• Subjects: Cancer research.; Molecular biology.; Cell biology.; Biomedical engineering.; Cancer Research.; Molecular Medicine.; Cell Biology.; Biomedical Engineering/Biotechnology.

This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics. Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms und...

Table of Contents:

• Prelims
• Drosophila model in cancer: an introduction
• Using Drosophila models and tools to understand the mechanisms of novel human cancer driver gene function
• The initial stage of tumorigenesis in Drosophila epithelial tissuesi
• Drosophila models of cell polarity and cell competition in tumourigenesis
• Two sides of the same coin - compensatory proliferation in regeneration and cancer
• P53 and apoptosis in the Drosophila model
• Autophagy and tumorigenesis in Drosophila
• Filling the gaps among obesity, the CDK8 module, and uterine tumors using Drosophila
• MicroRNAs in Drosophila cancer models
• Cancer Stem Cells and Stem Cell Tumors in Drosophila
• Drosophila as a model for tumor-induced organ wasting
• Drosophila melanogaster as a model system for human glioblastomas
• What Drosophila Can Teach Us About Radiation Biology of Human Cancers
• Drosophila based cancer drug discovery frameworkIn
• Index.