Persister Cells and Infectious Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Lewis, Kim (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Subjects: Medical microbiology.; Immunology.; Infectious diseases.; Medical Microbiology.; Infectious Diseases.

This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on...

Table of Contents:

• 1. Evolution under antibiotic treatments: interplay between antibiotic persistence, tolerance and resistance
• 2. Antibiotic persisters and relapsing Salmonella enterica infections
• 3. The Biology of Persister Cells in E. coli
• 4. Persister Formation and Antibiotic Tolerance of Chronic Infections
• 5. Persister formation driven by TisB-dependent membrane depolarization
• 6. Toxin-antitoxin systems and persistence
• 7. Nutrient depletion and bacterial persistence
• 8. Genetic determinants of persistence in Escherichia coli
• 9. Persister resuscitation
• 10. Host-pathogen interactions influencing Mycobacterium tuberculosis persistence and drug tolerance
• 11. Drug susceptibility of individual mycobacterial cells
• 12. Antimicrobial drug discovery against persisters. .