DNA Systems Under Internal and External Forcing An Exploration Using Coarse-Grained Modelling /

• Main Author: Engel, Megan Clare (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Nanoscale science.; Nanoscience.; Nanostructures.; Biomathematics.; Chemistry, Physical and theoretical.; Atomic structure .; Molecular structure .; Nanoscale Science and Technology.; Mathematical and Computational Biology.; Theoretical and Computational Chemistry.; Atomic/Molecular Structure and Spectra.

The interactions of DNA with force are central to manifold fields of inquiry, including the de novo design of DNA nanostructures, the use of DNA to probe the principles of biological self-assembly, and the operation of cellular nanomachines. This work presents a survey of three distinct ways coarse-...

Table of Contents:

• Introduction
• Simulation Methods
• Non-equilibrium bio-molecular unfolding under tension
• Force-induced unravelling of DNA origami
• Measuring internal forces in single-stranded DNA
• Conclusions
• Appendices.