Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis

• Corporate Author: SpringerLink (Online service)
• Other Authors: Devarajan, Padma V. (Editor, http://id.loc.gov/vocabulary/relators/edt), Dandekar, Prajakta (Editor, http://id.loc.gov/vocabulary/relators/edt), D'Souza, Anisha A. (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: AAPS Advances in the Pharmaceutical Sciences Series, 39
• Subjects: Pharmaceutical technology.; Pharmacy.; Cancer research.; Infectious diseases.; Pharmaceutical Sciences/Technology.; Cancer Research.; Infectious Diseases.

This book elaborates on various aspects of targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeti...

Table of Contents:

• Part 1-Introduction and overview
• Intracellular Delivery in Cancer and Infectious Diseases
• Intracellular Delivery by Receptor Mediated Endocytosis
• Part 2-Receptor and Receptor Medicated Endocytosis in Cancer
• Receptors Relevant for Cancer Therapeutics
• (chapters 3-8)
• Part 3-Receptors and Receptor Medicated Endocytosis in Infectious Diseases
• Receptors Relevant for Infectious Disease Therapeutics
• (chapters 9-13)
• Part 4-Common Receptors for Receptors and Receptor Mediated Endocytosis in Cancer and Infectious Diseases
• Chapters 14-17)
• Receptors Relevant for Cancer and Infectious Disease Therapeutics
• Part 5-Models for Evaluation of Targeted Delivery in Cancer and infectious Diseases
• In vitro and in vivo Models for Cancer and Infectious Diseases
• In vitro and in vivo Models for Infectious Diseases
• Part 6- Regulatory and Toxicity Issues
• Regulatory and Toxicity Issues in Targeted Delivery.