Drugs for HER-2-positive Breast Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Sibilia, Maria (Editor), Zielinski, Christoph C. (Editor), Bartsch, Rupert (Editor), Grunt, Thomas W. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Basel : Springer Basel, 2011.
• Series: Milestones in Drug Therapy
• Subjects: Medicine.; Cancer research.; Immunology.; Antibodies.; Pharmacology.; Internal medicine.; Oncology.; Biomedicine.; Pharmacology/Toxicology.; Cancer Research.; Internal Medicine.

Growth factor receptors have long been known to drive malignant transformation and cancer progression. The epidermal growth factor receptor (EGFR, ErbB, HER) system is likely the best described membrane receptor tyrosine kinase family in malignant tumors. With implementation of the growth-inhibitory...