Glutamate-based Therapies for Psychiatric Disorders

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Skolnick, Phil (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2010.
• Σειρά: Milestones in Drug Therapy
• Θέματα: Medicine.; Neurosciences.; Pharmacology.; Psychiatry.; Psychopharmacology.; Medicine & Public Health.; Pharmacology/Toxicology.

Both metabotropic and ionotropic glutamate receptors present attractive “druggable” targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injury to the t...

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• Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors
• Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders
• Activation of Group II Metabotropic Glutamate Receptors (mGluR2 and mGluR3) as a Novel Approach for Treatment of Schizophrenia
• mGluR1 Negative Allosteric Modulators: An Alternative Metabotropic Approach for the Treatment of Schizophrenia
• Metabotropic Glutamate Receptors as Targets for the Treatment of Drug and Alcohol Dependence
• Metabotropic Approaches to Anxiety.