Replicating Vaccines A New Generation /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Dormitzer, Philip R. (Επιμελητής έκδοσης), Mandl, Christian W. (Επιμελητής έκδοσης), Rappuoli, Rino (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel, 2011.
• Έκδοση: First.
• Σειρά: Birkhäuser Advances in Infectious Diseases
• Θέματα: Medicine.; Immunology.; Medical microbiology.; Vaccines.; Virology.; Biomedicine.; Medical Microbiology.; Vaccine.

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by e...

Πίνακας περιεχομένων:

• SECTION 1: Today’s Live Attenuated Vaccines
• Live Vaccines and their Role in Modern Vaccinology
• Live Attenuated Vaccines: Influenza, Rotavirus and Varicella Zoster
• Classical Live Viral Vaccines
• SECTION 2: Genetically Attenuated Micro-Organisms as Vaccines
• Recombinant Live Vaccines to Protect Against the Severe Acute Respiratory Syndrome Coronavirus
• Live Attenuated Shigella Vaccines. Is encouraging good enough?
• New generation BCG vaccines
• SECTION 3: Manipulating Host-Pathogen Interactions to Make Vaccines
• Basic Science Paves the Way to Novel Safe and Effective Pestivirus Vaccines
• Live Attenuated Influenza Virus Vaccines: NS1 Truncation as an Approach to Virus Attenuation Approaches
• An Attenuated Herpes implex Virus 1 Live Virus Vaccine Candidate that is Replication Competent but Defective in Epithelial Cell to Cell and Neuronal Spread
• RSV Deletion Mutant – Innate Immunity
• Live Attenuated Cholera Vaccines: Flagella and Reactogenicity
• SECTION 4: New Types of Replicating Vaccines
• Replication-defective Herpes simplex Virus Mutant Strains as Genital Herpes Vaccines and Vaccine Vectors
• Nucleic Acid-Based Infectious and Pseudo-Infectious Flavivirus Vaccines
• Application of Cleavage Activation Mutants of Influenza Virus as Live Vaccines
• Alphavirus Particle-based Vaccine Vectors
• Recombinant, Chimeric, Live, Attenuated Vaccines against Flaviviruses and Alphaviruses.