Signposts to Chiral Drugs Organic Synthesis in Action /

• Κύριοι συγγραφείς: Sunjic, Vitomir (Συγγραφέας), Parnham, Michael J. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel : Imprint: Springer, 2011.
• Θέματα: Medicine.; Pharmacology.; Pharmaceutical technology.; Organic chemistry.; Chemical engineering.; Medicinal chemistry.; Medical biochemistry.; Biomedicine.; Pharmacology/Toxicology.; Pharmaceutical Sciences/Technology.; Organic Chemistry.; Medicinal Chemistry.; Medical Biochemistry.; Industrial Chemistry/Chemical Engineering.

Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry. The book starts with an introduction treating the discovery and development o...

Πίνακας περιεχομένων:

• Organic synthesis in drug discovery and development
• Aliskiren fumarate
• (R)-K-13675
• Sitagliptin phosphate monohydrate
• Biaryl unit in valsartan and vancomycin
• 3-Amino-1,4-benzodiazepines
• Sertraline
• 1,2-Dihydroquinolines
• (-)-Menthol
• Fexofenadine hydrochloride
• Montelukast sodium
• Thiolactone peptides as antibacterial peptidomimetics
• Efavirenz
• Paclitaxel
• Neoglycoconjugate
• 12-Aza <epothilones.  .