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03083nam a22005535i 4500 |
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978-3-0348-0679-4 |
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DE-He213 |
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20151103123201.0 |
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130628s2013 sz | s |||| 0|eng d |
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|a 9783034806794
|9 978-3-0348-0679-4
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|a 10.1007/978-3-0348-0679-4
|2 doi
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|a 591.35
|2 23
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|a Barrett, Lucy W.
|e author.
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|a Untranslated Gene Regions and Other Non-coding Elements
|h [electronic resource] :
|b Regulation of Eukaryotic Gene Expression /
|c by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton.
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|a Basel :
|b Springer Basel :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a VIII, 56 p. 2 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a text file
|b PDF
|2 rda
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| 490 |
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|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
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|a Introduction -- Promoter -- 5’ Untranslated Region -- Structure -- Intronic Regions -- 3’ Untranslated Region -- Non-coding RNAs -- Conclusion.
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|a There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
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|a Life sciences.
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| 650 |
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|a Medical genetics.
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| 650 |
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|a Nucleic acids.
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| 650 |
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|a Plant genetics.
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| 650 |
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|a Animal genetics.
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| 650 |
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4 |
|a Life Sciences.
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| 650 |
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4 |
|a Animal Genetics and Genomics.
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| 650 |
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|a Plant Genetics & Genomics.
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| 650 |
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|a Gene Function.
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| 650 |
2 |
4 |
|a Nucleic Acid Chemistry.
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| 700 |
1 |
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|a Fletcher, Sue.
|e author.
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| 700 |
1 |
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|a Wilton, Steve D.
|e author.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 776 |
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8 |
|i Printed edition:
|z 9783034806787
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| 830 |
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|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/978-3-0348-0679-4
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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