Gamma-Glutamyl Transpeptidases Structure and Function /

• Κύριοι συγγραφείς: Castellano, Immacolata (Συγγραφέας), Merlino, Antonello (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel : Imprint: Springer, 2013.
• Σειρά: SpringerBriefs in Biochemistry and Molecular Biology,
• Θέματα: Life sciences.; Human physiology.; Biochemical engineering.; Enzymology.; Life Sciences.; Human Physiology.; Biochemical Engineering.

 Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptid...

Πίνακας περιεχομένων:

•  1 Introduction
• 2 Occurrence, genes and gene expression
• 3 Structure and function of γ-GTs
• 4 Autoprocessing and reaction mechanism of γ-GTs
• 5 γ-GT in bioclinical
• 6 γ-GTs: biotechnological and biomedical applications
• 7 Conclusions
• References.