Genomics of Pattern Recognition Receptors Applications in Oncology and Cardiovascular Diseases /

• Κύριοι συγγραφείς: Kutikhin, Anton G. (Συγγραφέας), Yuzhalin, Arseniy E. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel : Imprint: Springer, 2013.
• Θέματα: Life sciences.; Cancer research.; Human genetics.; Immunology.; Cardiology.; Oncology.; Proteins.; Life Sciences.; Receptors.; Cancer Research.; Human Genetics.
• Φυσική περιγραφή: XI, 185 p. online resource.
• ISBN: 9783034806886

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.