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02976nam a22005535i 4500 |
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978-3-0348-0688-6 |
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DE-He213 |
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20151218121823.0 |
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cr nn 008mamaa |
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130828s2013 sz | s |||| 0|eng d |
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|a 9783034806886
|9 978-3-0348-0688-6
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|a 10.1007/978-3-0348-0688-6
|2 doi
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|a 572.696
|2 23
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|a Kutikhin, Anton G.
|e author.
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|a Genomics of Pattern Recognition Receptors
|h [electronic resource] :
|b Applications in Oncology and Cardiovascular Diseases /
|c by Anton G. Kutikhin, Arseniy E. Yuzhalin.
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|a Basel :
|b Springer Basel :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XI, 185 p.
|b online resource.
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|a text
|b txt
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|a online resource
|b cr
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|a text file
|b PDF
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|a The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go.
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|a This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
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|a Life sciences.
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|a Cancer research.
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| 650 |
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|a Human genetics.
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| 650 |
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|a Immunology.
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| 650 |
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|a Cardiology.
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| 650 |
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|a Oncology.
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| 650 |
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|a Proteins.
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| 650 |
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4 |
|a Life Sciences.
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| 650 |
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|a Receptors.
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| 650 |
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|a Immunology.
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| 650 |
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|a Cancer Research.
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| 650 |
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|a Human Genetics.
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| 650 |
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|a Oncology.
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| 650 |
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|a Cardiology.
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| 700 |
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|a Yuzhalin, Arseniy E.
|e author.
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| 710 |
2 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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| 776 |
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|i Printed edition:
|z 9783034806879
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| 856 |
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|u http://dx.doi.org/10.1007/978-3-0348-0688-6
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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