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03464nam a22005295i 4500 |
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978-3-0348-0706-7 |
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DE-He213 |
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20151030061528.0 |
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131122s2014 sz | s |||| 0|eng d |
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|a 9783034807067
|9 978-3-0348-0706-7
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|a 10.1007/978-3-0348-0706-7
|2 doi
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|a RM1-950
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|a MMG
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|a MED071000
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|a 615
|2 23
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|a Drugs Targeting B-Cells in Autoimmune Diseases
|h [electronic resource] /
|c edited by Xavier Bosch, Manuel Ramos-Casals, Munther A Khamashta.
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1 |
|a Basel :
|b Springer Basel :
|b Imprint: Springer,
|c 2014.
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300 |
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|a XI, 292 p. 3 illus., 2 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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|a Milestones in Drug Therapy,
|x 2296-6056
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|a Historic outline of the development of drugs targeting B-cells -- Understanding B-cell biology -- Pharmacological effects and mechanisms of action of agents blocking B cells -- Systemic lupus erythematosus: direct B-cell blocking -- Systemic lupus erythematosus: indirect B-cell blocking -- B-cell targeted therapies in rheumatoid arthritis -- B-cell targeted therapies in Primary Sjögren Syndrome -- Targeting B cells in ANCA-associated vasculitis -- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies -- B-cell targeted therapies in cryoglobulinemia -- B-cell targeted therapies in autoimmune cytopenias and thrombosis -- Targeting B cells in neurological autoimmune diseases -- Targeting B cells in other systemic autoimmune diseases -- Safety of B-cell targeted therapies -- The future potential of biosimilars targeting B-cells.
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|a This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.
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650 |
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|a Medicine.
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650 |
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|a Immunology.
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650 |
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|a Pharmacology.
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650 |
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|a Internal medicine.
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650 |
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|a Rheumatology.
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650 |
1 |
4 |
|a Biomedicine.
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650 |
2 |
4 |
|a Pharmacology/Toxicology.
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650 |
2 |
4 |
|a Immunology.
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650 |
2 |
4 |
|a Rheumatology.
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650 |
2 |
4 |
|a Internal Medicine.
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700 |
1 |
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|a Bosch, Xavier.
|e editor.
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700 |
1 |
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|a Ramos-Casals, Manuel.
|e editor.
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700 |
1 |
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|a Khamashta, Munther A.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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776 |
0 |
8 |
|i Printed edition:
|z 9783034807050
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830 |
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0 |
|a Milestones in Drug Therapy,
|x 2296-6056
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856 |
4 |
0 |
|u http://dx.doi.org/10.1007/978-3-0348-0706-7
|z Full Text via HEAL-Link
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912 |
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|a ZDB-2-SBL
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950 |
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|a Biomedical and Life Sciences (Springer-11642)
|