Drugs Targeting B-Cells in Autoimmune Diseases

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Bosch, Xavier (Επιμελητής έκδοσης), Ramos-Casals, Manuel (Επιμελητής έκδοσης), Khamashta, Munther A. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel : Imprint: Springer, 2014.
• Σειρά: Milestones in Drug Therapy,
• Θέματα: Medicine.; Immunology.; Pharmacology.; Internal medicine.; Rheumatology.; Biomedicine.; Pharmacology/Toxicology.; Internal Medicine.

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are dis...

Πίνακας περιεχομένων:

• Historic outline of the development of drugs targeting B-cells
• Understanding B-cell biology
• Pharmacological effects and mechanisms of action of agents blocking B cells
• Systemic lupus erythematosus: direct B-cell blocking
• Systemic lupus erythematosus: indirect B-cell blocking
• B-cell targeted therapies in rheumatoid arthritis
• B-cell targeted therapies in Primary Sjögren Syndrome
• Targeting B cells in ANCA-associated vasculitis
• B-cell targeted therapies in systemic sclerosis and inflammatory myopathies
• B-cell targeted therapies in cryoglobulinemia
• B-cell targeted therapies in autoimmune cytopenias and thrombosis
• Targeting B cells in neurological autoimmune diseases
• Targeting B cells in other systemic autoimmune diseases
• Safety of B-cell targeted therapies
• The future potential of biosimilars targeting B-cells.