Mathematical Modelling of the Cell Cycle Stress Response

• Main Author: Radmaneshfar, Elahe (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2014.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Physics.; Bioinformatics.; Cell cycle.; Biomathematics.; Biophysics.; Physics of the Cell.; Cell Cycle Analysis.; Physiological, Cellular and Medical Topics.; Computational Biology/Bioinformatics.; Complex Networks.

The cell cycle is a sequence of biochemical events that are controlled by complex but robust molecular machinery. This enables cells to achieve accurate self-reproduction under a broad range of conditions. Environmental changes are transmitted by molecular signaling networks, which coordinate their...

Table of Contents:

• A biological overview of the cell cycle and its response to osmotic stress and the α-factor
• ODE model of the cell cycle response to osmotic stress
• Boolean model of the cell cycle response to stress
• Conclusion
• List of equations, parameters and initial conditions
• Effect of methods of update on existence of fixed points.