A Systems Biology Approach to Study Metabolic Syndrome

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Orešič, Matej (Επιμελητής έκδοσης), Vidal-Puig, Antonio (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2014.
• Θέματα: Medicine.; Human physiology.; Molecular biology.; Biomedicine.; Biomedicine general.; Molecular Medicine.; Human Physiology.

The aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology...

Πίνακας περιεχομένων:

• The metabolic syndrome and its complex pathophysiology
• Systems biology in human health and disease
• The liver in metabolic syndrome
• Role of adipose tissue in the pathogenesis and treatment of metabolic syndrome
• The beta cell in metabolic syndrome
• The skeletal muscle in metabolic syndrome
• The central nervous system in metabolic syndrome
• Lipid metabolism in metabolic syndrome
• Gut microbiota in metabolic syndrome
• Proteomics in the systems-level study of the metabolic syndrome
• Metabolomics in the systems-level study of the metabolic syndrome
• Fluxomics
• In vitro colon model to study metabolic syndrome
• Genome-scale modeling of tissue and cancer metabolism
• Modeling of lipid membranes and lipoproteins
• Computational statistics approaches to study metabolic syndrome
• Towards modeling of metabolic syndrome: Tissue crosstalk in lipid spillover.