Structural and Functional Characterization of the Immunoproteasome

• Main Author: Huber, Eva Maria (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2013.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Analytical chemistry.; Medicinal chemistry.; Proteins.; Analytical Chemistry.; Protein Science.; Medicinal Chemistry.

In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscop...

Table of Contents:

• Introduction
• Objective
• Materials and Methods
• Results
• Discussion
• Appendix.