Mechanisms of Atrial Arrhythmias Insights from the Development of a Biophysically Detailed Model of the Human Atria /

• Κύριος συγγραφέας: Colman, Michael A. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2014.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Physics.; Cardiology.; Bioinformatics.; Computational biology.; Mathematical physics.; Biophysics.; Biological physics.; Biophysics and Biological Physics.; Computer Appl. in Life Sciences.; Numerical and Computational Physics.; Mathematical Applications in the Physical Sciences.

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac elec...

Πίνακας περιεχομένων:

• Introduction
• Background
• Development of a new model for simulating the electrical action potentials of human atrial myocytes
• Development of a family of regional cell models
• Autonomic regulation and pathophysiological remodelling
• 3D Anatomical Modelling of the Atria
• Pacemaking and autonomic regulation in the 3D sinoatrial node and atria
• Atrial Fibrillation
• Discussion.