MicroRNAs: Key Regulators of Oncogenesis

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Babashah, Sadegh (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2014.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Gene expression.; Medical genetics.; Drug resistance.; Molecular biology.; Biomedicine.; Cancer Research.; Human Genetics.; Gene Expression.; Gene Function.; Molecular Medicine.; Drug Resistance.

Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as...

Πίνακας περιεχομένων:

• Preface
• Part I MicroRNAs: biology and implications in cancer
• MicroRNAs and cancer: an overview
• Epigenetics and microRNA in cancer
• MicroRNA, diet and cancer chemoprevention
• MicroRNAs and energy metabolism in cancer cells
• MicroRNAs and solid tumors
• MicroRNAs and blood cancers
• MicroRNAs and oncogenic human viruses
• MicroRNAs linking cancer and inflammation: focus on liver cancer
• MicroRNAs and regulatory pathways in tumorigenesis
• MicroRNA-modulated apoptotic and autophagic signaling networks in cancer
• MicroRNAs and cancer drug resistance and drug sensitivity
• The biological roles of microRNAs in cancer stem cells
• Part II MicroRNAs and their clinical implications
• MicroRNAs and clinical implications in cancer
• MicroRNA expression profiling and its clinical impact in breast cancer
• MicroRNAs and their clinical impact on resistance to anticancer treatment
• Nanocarriers and microRNA-based scenarios for cancer therapy
• Challenges and strategies for pulmonary delivery of microRNA-based therapeutics
• Abbreviations
• Index.