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02922nam a22004815i 4500 |
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978-3-319-04462-0 |
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DE-He213 |
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20151030061215.0 |
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cr nn 008mamaa |
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140305s2014 gw | s |||| 0|eng d |
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|a 9783319044620
|9 978-3-319-04462-0
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|a 10.1007/978-3-319-04462-0
|2 doi
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|d GrThAP
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|a QD415-436
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|a PNN
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|a SCI013040
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|a 547
|2 23
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|a Lee, Kiyoun.
|e author.
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|a Stereoselective Syntheses of Tetrahydropyrans
|h [electronic resource] :
|b Applications to the Synthesis of (+)-Leucascandrolide A, (+)-Dactylolide and (±)-Diospongin A /
|c by Kiyoun Lee.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2014.
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|a XIX, 184 p. 256 illus., 12 illus. in color.
|b online resource.
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|a text
|b txt
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|a computer
|b c
|2 rdamedia
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|a online resource
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|a text file
|b PDF
|2 rda
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|a Springer Theses, Recognizing Outstanding Ph.D. Research,
|x 2190-5053
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|a Introduction -- Significance -- General Approaches to the Synthesis of Substituted Tetrahydropyrans -- Stereoselective Synthesis of Tetrahydropyrans via Tandem and Organocatalytic Oxa-Conjugate Addition Reactions -- Introduction -- Preliminary Study -- Result and Discussion -- Synthesis of 4-Hydroxy-2,6-cis-Tetrahydropyrans via Tandem Cross-Metathesis/Thermal SN2′ Reaction.
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|a In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and (±)-diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology. .
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|a Chemistry.
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|a Pharmaceutical technology.
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|a Organic chemistry.
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|a Chemical engineering.
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|a Chemistry.
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|a Organic Chemistry.
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|a Pharmaceutical Sciences/Technology.
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|a Industrial Chemistry/Chemical Engineering.
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9783319044613
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|a Springer Theses, Recognizing Outstanding Ph.D. Research,
|x 2190-5053
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|u http://dx.doi.org/10.1007/978-3-319-04462-0
|z Full Text via HEAL-Link
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|a ZDB-2-CMS
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|a Chemistry and Materials Science (Springer-11644)
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