Stereoselective Syntheses of Tetrahydropyrans Applications to the Synthesis of (+)-Leucascandrolide A, (+)-Dactylolide and (±)-Diospongin A /

• Main Author: Lee, Kiyoun (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2014.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Pharmaceutical technology.; Organic chemistry.; Chemical engineering.; Organic Chemistry.; Pharmaceutical Sciences/Technology.; Industrial Chemistry/Chemical Engineering.

In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leu...

Table of Contents:

• Introduction
• Significance
• General Approaches to the Synthesis of Substituted Tetrahydropyrans
• Stereoselective Synthesis of Tetrahydropyrans via Tandem and Organocatalytic Oxa-Conjugate Addition Reactions
• Introduction
• Preliminary Study
• Result and Discussion
• Synthesis of 4-Hydroxy-2,6-cis-Tetrahydropyrans via Tandem Cross-Metathesis/Thermal SN2′ Reaction.