Sickle Cell Anemia From Basic Science to Clinical Practice /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Costa, Fernando Ferreira (Επιμελητής έκδοσης), Conran, Nicola (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Θέματα: Medicine.; Internal medicine.; Hematology.; Medical biochemistry.; Medicine & Public Health.; Internal Medicine.; Medical Biochemistry.; Medicine/Public Health, general.

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated...

Πίνακας περιεχομένων:

• Chapter 1 Hemoglobin: Structure, Synthesis and Oxygen Transport
• Chapter 2 Sickle cell Anemia: History and Epidemiology
• Chapter 3 Overview of Sickle Cell Anemia Pathophysiology
• Chapter 4 Red Blood Cells and the Vaso-occlusive Process
• Chapter 5 Leukocytes in the vaso-occlusive process
• Chapter 6 Hypercoagulability and Sickle Cell Disease
• Chapter 7 Cardiovascular Adaptations to Anemia and the Role of Vascular Endothelium in Sickle Cell Disease Pathophysiology
• Chapter 8 Inflammation and Sickle Cell Anemia
• Chapter 9 Clinical Manifestations of Sickle Cell Anemia: Infants and Children
• Chapter 10 Treatment of Childhood Sickle Cell Disease
• Chapter 11 Priapism in Sickle Cell Disease: New aspects of pathophysiology
• Chapter 12 Clinical Manifestations and Treatment of Adult Sickle Cell
• Chapter 13 Hemoglobin Sβ Thalassemia, SC Disease and SD Disease: Clinical and Laboratorial Aspects
• Chapter 14 Sickle Cell Disease in Africa and the Arabian Peninsula: Current Management and Challenges
• Chapter 15 Genetic Factors modifying sickle cell disease severity
• Chapter 16 Future Perspectives for the Treatment of Sickle Cell.