High-Performance Computational Solutions in Protein Bioinformatics

Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation leve...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Mrozek, Dariusz (Συγγραφέας)
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2014.
Σειρά:SpringerBriefs in Computer Science,
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03263nam a22005535i 4500
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003 DE-He213
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020 |a 9783319069715  |9 978-3-319-06971-5 
024 7 |a 10.1007/978-3-319-06971-5  |2 doi 
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100 1 |a Mrozek, Dariusz.  |e author. 
245 1 0 |a High-Performance Computational Solutions in Protein Bioinformatics  |h [electronic resource] /  |c by Dariusz Mrozek. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2014. 
300 |a XIX, 109 p. 56 illus., 21 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a SpringerBriefs in Computer Science,  |x 2191-5768 
505 0 |a Formal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling -- Multithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks. 
520 |a Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels, and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics, and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases. 
650 0 |a Computer science. 
650 0 |a Microprocessors. 
650 0 |a Computer communication systems. 
650 0 |a Bioinformatics. 
650 0 |a Proteins. 
650 0 |a Biomathematics. 
650 1 4 |a Computer Science. 
650 2 4 |a Computational Biology/Bioinformatics. 
650 2 4 |a Computer Communication Networks. 
650 2 4 |a Protein Structure. 
650 2 4 |a Bioinformatics. 
650 2 4 |a Processor Architectures. 
650 2 4 |a Mathematical and Computational Biology. 
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776 0 8 |i Printed edition:  |z 9783319069708 
830 0 |a SpringerBriefs in Computer Science,  |x 2191-5768 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-06971-5  |z Full Text via HEAL-Link 
912 |a ZDB-2-SCS 
950 |a Computer Science (Springer-11645)