Biopsy Diagnosis of Peripheral Neuropathy

• Main Authors: Bilbao, Juan M. (Author), Schmidt, Robert E. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 2nd ed. 2015.
• Subjects: Medicine.; Neurosciences.; Neurology.; Neurosurgery.; Pathology.; Medicine & Public Health.

 Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible. 

 Introduction and Clinical Correlation -- Normal Peripheral Nerve Structure -- Basic Pathological Mechanisms -- Vasculitic Neuropathy -- Diabetic neuropathies -- Skin Biopsies -- Metabolic Neuropathies -- Inflammatory and Immune-Mediated Neuropathies -- Neuropathies Associated with Infectious Diseases -- Amyloid neuropathy -- Genetic Neuropathies -- Dysproteinemias -- Toxin-induced neuropathies -- Miscellaneous neuropathies.