ADAMTS13 Biology and Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Rodgers, George M. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Έκδοση: 1st ed. 2015.
• Θέματα: Life sciences.; Hematology.; Proteomics.; Cell biology.; Life Sciences.; Cell Biology.

This comprehensive volume discusses the protease ADAMTS13, summarizing the current status of basic and clinical research. The nine authoritative chapters begin with a historical perspective followed by exploration of the biochemistry and structure-function relationships of ADAMTS13 as well as its no...

Πίνακας περιεχομένων:

• 1. A13: Structure and function
• 2. A13: The von Willebrand factor cleaving protease
• 3. A13: Angiogenesis and other biologic activities
• 4. A13:  Assays
• 5. Inherited A13 deficiency (Upshaw-Schulman Syndrome)
• 6. Acquired A13 deficiency (TTP)
• 7. Related thrombotic microangiopathies
• 8. Future directions.