Mathematical Modelling of Chromosome Replication and Replicative Stress

• Κύριος συγγραφέας: Karschau, Jens (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Physics.; Genetic engineering.; Nucleic acids.; Biophysics.; Statistical physics.; Dynamical systems.; Physics of the Cell.; Statistical Physics, Dynamical Systems and Complexity.; Nucleic Acid Chemistry.; Genetic Engineering.; Numerical and Computational Physics.

DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next, and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism o...

Πίνακας περιεχομένων:

• Introduction
• Optimal Origin Placement for Minimal Replication Time
• Actively Replicating Domains Randomly Associate into Replication Factories
• Summary and Conclusions.