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|a 9783319107714
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|a 10.1007/978-3-319-10771-4
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|a Endogenous ADP-Ribosylation
|h [electronic resource] /
|c edited by Friedrich Koch-Nolte.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2015.
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|a VIII, 213 p.
|b online resource.
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|a text
|b txt
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|a computer
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|a text file
|b PDF
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 384
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|a The natural history of ADP-ribosyltransferases and the ADP ribosylation system -- Identification and Analysis of ADP-ribosylated Proteins -- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine -- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein -- Regulation of nitrogenase by reversible mono-ADP-ribosylation -- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells -- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish -- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family -- Function and regulation of the mono-ADP-ribosyltransferase ARTD10 -- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-β1 mono-ADP-ribosylation by ARTD15.
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| 520 |
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|a This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: · Evolution and detection of endogenous ADP-ribosylation · ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) · ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.
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| 650 |
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|a Medicine.
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| 650 |
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|a Immunology.
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| 650 |
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|a Medical microbiology.
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|a Pharmacology.
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|a Biomedicine.
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|a Pharmacology/Toxicology.
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|a Medical Microbiology.
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| 650 |
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|a Immunology.
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| 700 |
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|a Koch-Nolte, Friedrich.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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| 776 |
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|i Printed edition:
|z 9783319107707
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| 830 |
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 384
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| 856 |
4 |
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|u http://dx.doi.org/10.1007/978-3-319-10771-4
|z Full Text via HEAL-Link
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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