The Networking of Chaperones by Co-chaperones Control of Cellular Protein Homeostasis /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Blatch, Gregory Lloyd (Επιμελητής έκδοσης), Edkins, Adrienne Lesley (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: Subcellular Biochemistry, 78
• Θέματα: Medicine.; Life sciences.; Biochemistry.; Biomedicine.; Biomedicine general.; Life Sciences, general.; Biochemistry, general.

Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecul...

Πίνακας περιεχομένων:

• Preface
• List of Contributors- About the Editors- GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: Nucleotide exchange factors for Hsp70 molecular chaperones
• Functions of the Hsp90-Binding FKBP Immunophilins
• Hsp70/Hsp90 organising protein (Hop): beyond interactions with chaperones and prion proteins
• Specification of Hsp70 function by Type I and Type II Hsp40
• Cdc37 as a Co-chaperone to Hsp90
• p23 and Aha1- UCS proteins: chaperones for myosin and co-chaperones for Hsp90
• Chaperonin - Co-chaperonin Interactions
• Co-chaperones of the mammalian endoplasmic reticulum
• The evolution and function of co-chaperones in mitochondria
• CHIP: a co-chaperone for degradation by the proteasome
• The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease
• Index.