An Information Technology Framework for Predictive, Preventive and Personalised Medicine A Use-Case with Hepatocellular Carcinoma /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Berliner, Leonard (Επιμελητής έκδοσης), Lemke, Heinz U. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: Advances in Predictive, Preventive and Personalised Medicine, 8
• Θέματα: Medicine.; Health informatics.; Hepatology.; Oncology.; Data mining.; Computer simulation.; Medicine & Public Health.; Health Informatics.; Data Mining and Knowledge Discovery.; Simulation and Modeling.
• Φυσική περιγραφή: XX, 130 p. 23 illus., 15 illus. in color. online resource.
• ISBN: 9783319121666
• ISSN: 2211-3495 ;

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.