Molecular Therapies of Cancer

• Main Author: Weber, Georg F. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Subjects: Medicine.; Cancer research.; Laboratory medicine.; Oncology.; Biomedicine.; Cancer Research.; Laboratory Medicine.

 Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies. 

 DNA Damaging Drugs -- Drugs that Suppress Proliferation -- Molecular Inhibitors of Growth Signals -- Anti-Metastasis Therapy -- Induction of Senesence -- Combination Chemotherapy -- Gene Therapy -- Drugs with Diverse Modes of Action -- Hormone Therapy -- Immunotherapy -- Anti-Angiogenesis -- Drug Delivery and Drug Transport -- Drug Metabolism -- Prodrug Activation -- Drug Resistance -- Protection from Adverse Effects -- Pain Management -- Preventative Treatment.