Free Radicals in ENT Pathology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Miller, Josef (Επιμελητής έκδοσης), Le Prell, Colleen G. (Επιμελητής έκδοσης), Rybak, Leonard (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Humana Press, 2015.
• Σειρά: Oxidative Stress in Applied Basic Research and Clinical Practice,
• Θέματα: Life sciences.; Otorhinolaryngology.; Pathology.; Oxidative stress.; Life Sciences.; Oxidative Stress.

This comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the challenges to translation, and identi...

Πίνακας περιεχομένων:

• 1. Introduction
• Section 1: Basic Science of Free Radical Biology in ENT
• 2. Free radicals and oxidative stress: Basic concepts and misconceptions
• 3. A Question of Balance:  Free Radicals and Cochlear Homeostasis
• 4. Antioxidants and their effect on stress-induced pathology in the inner ear
• Section 2: Epidemiology of Hearing Loss
• 5. Role of free radicals in hearing loss due to heavy metals
• 6. The role of nutrition in healthy hearing: human evidence
• Section 3: Oxidative Stress and Noise-Induced Hearing Loss
• 7. Basic mechanisms underlying noise-induced hearing loss
• 8. Oxidative stress in noise-induced hearing loss
• 9. Strategies for evaluating antioxidant efficacy in clinical trials assessing prevention of noise-induced hearing loss
• Section 4: Oxidative Stress and Drug-Induced Hearing Loss
• 10. Aminoglycoside-induced oxidative stress: pathways and protection
• 11. Hearing loss after cis-platin: oxidative stress pathways and potential for protection
• 12. Assessment of interventions to prevent drug-induced hearing loss (DIHL)
• Section 5: Oxidative Stress and Age-Related Hearing Loss
• 13. Age-related hearing loss: biochemical pathways and molecular targets
• 14. Genetics and age-related hearing loss
• 15. Mechanisms of age-related hearing loss
• 16. Interventions to prevent age-related hearing loss
• Section 6. Hereditary Hearing Loss
• 17. Genes and hearing loss: relationship to oxidative stress and free radical formation
• 18. Strategies for the treatment of hereditary hearing loss
• Section 7: Cochlear Implants, Radiation, Trauma and Other Stress Factors
• 19. Loss of Residual Hearing Initiated by Cochlear Implantation: Role of Inflammation-Initiated Cell
• 20. Role of oxidative stress in sudden hearing loss and Meniere’s disease
• Section 8: Head and Neck
• 21. Role of free radicals in head and neck pathology
• 22. Free radicals and sleep apnea
• 23. Free radicals in nasal and paranasal disease
• 24. Conclusion.