IgE Antibodies: Generation and Function

• Corporate Author: SpringerLink (Online service)
• Other Authors: Lafaille, Juan J. (Editor), Curotto de Lafaille, Maria A. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Series: Current Topics in Microbiology and Immunology, 388
• Subjects: Medicine.; Antibodies.; Molecular biology.; Parasitology.; Allergy.; Biomedicine.; Molecular Medicine.; Allergology.

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and...

Table of Contents:

• Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses
• Molecular Mechanisms of IgE Class Switch Recombination
• Anti-IgE Therapy: Clinical Utility and Mechanistic Insights
• New Insights on the Signaling and Function of the High Affinity Receptor for IgE
• Helminth-Induced IgE and Protection Against Allergic Disorders
• IgE Immunotherapy Against Cancer.