Pre-Analytics of Pathological Specimens in Oncology

This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pat...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Dietel, Manfred (Επιμελητής έκδοσης), Wittekind, Christian (Επιμελητής έκδοσης), Bussolati, Gianni (Επιμελητής έκδοσης), Winterfeld, Moritz von (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
Σειρά:Recent Results in Cancer Research, 199
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 1 0 |a Pre-Analytics of Pathological Specimens in Oncology  |h [electronic resource] /  |c edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz von Winterfeld. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2015. 
300 |a VI, 133 p. 65 illus., 61 illus. in color.  |b online resource. 
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490 1 |a Recent Results in Cancer Research,  |x 0080-0015 ;  |v 199 
505 0 |a What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics – Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge.  . 
520 |a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up. 
650 0 |a Medicine. 
650 0 |a Laboratory medicine. 
650 0 |a Oncology. 
650 0 |a Pathology. 
650 0 |a Surgery. 
650 1 4 |a Medicine & Public Health. 
650 2 4 |a Oncology. 
650 2 4 |a Pathology. 
650 2 4 |a Surgery. 
650 2 4 |a Laboratory Medicine. 
700 1 |a Dietel, Manfred.  |e editor. 
700 1 |a Wittekind, Christian.  |e editor. 
700 1 |a Bussolati, Gianni.  |e editor. 
700 1 |a Winterfeld, Moritz von.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783319139562 
830 0 |a Recent Results in Cancer Research,  |x 0080-0015 ;  |v 199 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-13957-9  |z Full Text via HEAL-Link 
912 |a ZDB-2-SME 
950 |a Medicine (Springer-11650)