Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells Mathematical Modeling and Experimental Observations /

• Κύριος συγγραφέας: Tavassoly, Iman (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Materials science.; Cancer research.; Bioinformatics.; Cell biology.; Biophysics.; Biological physics.; Biomaterials.; Materials Science.; Computational Biology/Bioinformatics.; Cancer Research.; Cell Biology.; Biophysics and Biological Physics.

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheosta...