Preventive and Predictive Genetics: Towards Personalised Medicine

• Corporate Author: SpringerLink (Online service)
• Other Authors: Grech, Godfrey (Editor), Grossman, Iris (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Series: Advances in Predictive, Preventive and Personalised Medicine, 9
• Subjects: Medicine.; Human genetics.; Drug resistance.; Molecular biology.; Pharmacology.; Systems biology.; Medical education.; Biomedicine.; Molecular Medicine.; Medical Education.; Systems Biology.; Human Genetics.; Pharmacology/Toxicology.; Drug Resistance.

Traditionally, medical research comprised of the identification of the pathological causes of a disease, its epidemiology and empirical investigation of treatment response. Intensive genetic research, marked by the completion of the human genome project in 2003, heralded a new era in medical researc...

Table of Contents:

• Introduction
• Preventive and Predictive Genetics: A perspective
• Roadmap to Drug Development Enabled by Pharmacogenetics
• Preventative and Predictive Genetics: Towards Personalised Medicine
• Pharmacokinetics and Pharmacogenetics: bringing the magic bullet closer to reality
• Pharmacogenetics of Adverse Drug Reactions
• Pharmacogenomics for haemoglobinopathies therapeutics
• Pharmacogenetics of Neurodegenerative Disorders
• Pharmacogenetics of asthma
• Pharmacogenetics and antineoplastic therapies
• Pharmacogenetics of coumarin anticoagulant therapy
• Implementation of Genomic Medicine: tools and challenges
• Ethical Considerations in the Genomic Era
• Index.