Branching Process Models of Cancer

• Main Author: Durrett, Richard (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Series: Mathematical Biosciences Institute Lecture Series ; 1.1
• Subjects: Mathematics.; Cancer research.; Probabilities.; Biomathematics.; Probability Theory and Stochastic Processes.; Mathematical and Computational Biology.; Cancer Research.

This volume develops results on continuous time branching processes and applies them to study rate of tumor growth, extending classic work on the Luria-Delbruck distribution. As a consequence, the authors calculate the probability that mutations that confer resistance to treatment are present at det...