Mathematical Modeling and Scale-Up of Liquid Chromatography With Application Examples /

• Main Author: Gu, Tingyue (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 2nd ed. 2015.
• Subjects: Chemistry.; Chromatography.; Biochemical engineering.; Chemoinformatics.; Chemical engineering.; Computer Applications in Chemistry.; Industrial Chemistry/Chemical Engineering.; Biochemical Engineering.

Tingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced sinc...

Table of Contents:

• Introduction
• Literature Review
• General Multicomponent Rate Models for Column Liquid Chromatography
• Parameter Estimation
• Mass Transfer Effects in Liquid Chromatography Simulation
• Interference Effects in Multicomponent Chromatography
• System Peaks in Multicomponent Elution
• Modeling and Scale-up of Size Exclusion Chromatography
• Modeling of LC with cored beads
• Modeling of Slow Kinetics and Affinity Chromatography
• Multicomponent Adsorption with Uneven Saturation Capacities
• Modeling of Multicomponent Gradient Elution
• Modeling of Ion-Exchange Chromatography
• Multicomponents Radial Flow Chromatography.