Molecular Oncology Testing for Solid Tumors A Pragmatic Approach /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Idowu, Michael Ola (Editor), Dumur, Catherine Isabelle (Editor), Garrett, Carleton Theodore (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Subjects: Medicine.; Oncology.; Pathology.; Medicine & Public Health.

This text is designed to present an up-to-date practical approach to molecular testing in an easy to understand format. Emphasis is placed on molecular testing for solid tumors, while underscoring the following: i) the crucial role of pathologists in ensuring specimen adequacy for molecular testing;...

Table of Contents:

• Part I. Overview of Basic Cellular Biology
• 1. Normal molecular biology and definition of terms
• 2. Pathologic changes: Chromosomes, genes, DNA, RNA and proteins
• 3. Standard nomenclature - introduction and brief overview
• Part II. Molecular Oncology Methodology
• 4. General principles of Oncology testing
• 5. Molecular methodologies
• 6. General principles of validating a molecular test
• Part III. Molecular testing in Solid Tumors
• 7. Lung and mediastinum
• 8. Breast
• 9. Head and neck (salivary glands)
• 10. Thyroid and parathyroid (endocrine)
• 11. Gastrointestinal and Pancreatobiliary
• 12. Soft tissue
• 13. Genitourinary system
• 14. Central Nervous System
• 15. Skin and adnexa
• 16. Common Hereditary Cancer Syndromes
• Part IV. The future is here
• 17. Application of next generation sequencing
• Part V. Quality Assurance and Regulatory affairs
• 18. Quality Assurance - pre-analytic, analytic and post-analytic
• 19. Regulatory affairs (including accreditation)
• 20. Coding and re-imbursement.