The BRICHOS Domain Its Proproteins and Functions /

• Κύριοι συγγραφείς: Presto, Jenny (Συγγραφέας), Johansson, Jan (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: SpringerBriefs in Molecular Science,
• Θέματα: Chemistry.; Bioorganic chemistry.; Proteins.; Bioorganic Chemistry.; Protein Structure.

This Brief summarizes the current research on the novel BRICHOS domain, which is a chaperone domain found in a variety of proteins and is shown to exhibit anti-amyloidogenic chaperone-like functions. The BRICHOS domain is defined from sequence similarities, lacks established physiological function(s...

Πίνακας περιεχομένων:

• Introduction to BRICHOS Superfamily
• BRICHOS in proSP-C
• Proteins with a BRICHOS Domain
• Aβ Amyloid Formation in Alzheimer's disease
• In vivo Effect of BRICHOS on Aβ Aggregation and Toxicity.