Stem Cells in Modeling Human Genetic Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Zatz, Mayana (Editor), Keith Okamoto, Oswaldo (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Series: Stem Cell Biology and Regenerative Medicine,
• Subjects: Life sciences.; Human genetics.; Stem cells.; Regenerative medicine.; Tissue engineering.; Life Sciences.; Stem Cells.; Regenerative Medicine/Tissue Engineering.; Human Genetics.

Using stem cells to investigate currently untreatable human genetic diseases is the focus of this book. Several applications of the Nobel-Prize winning, revolutionary iPS cell technology are explored in detail, including in schizophrenia, autism, Huntington’s disease, Alzheimer’s disease, spinocereb...

Table of Contents:

• Modeling Fragile X Syndrome in Human Pluripotent Cells
• Induced Pluripotent Stem Cells in Familial Dilated Cardiomyopathy.- Induced Pluripotent Stem Cells and Amyotrophic Lateral Sclerosis
• IPS Cells and Spinocerebellar Ataxia
• Induced Pluripotent Stem Cells and Vascular Disease
• iPS Cells and Cardiomyopathies
• Cancer Stem Cells and Chemoresistance
• Stem Cells in Autism Spectrum Disorders.