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|a 9783319183657
|9 978-3-319-18365-7
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|a 10.1007/978-3-319-18365-7
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|a Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases
|h [electronic resource] /
|c edited by Neville Vassallo.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2015.
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| 300 |
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|a VII, 163 p. 41 illus., 26 illus. in color.
|b online resource.
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|a text
|b txt
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|a computer
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|a online resource
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|a text file
|b PDF
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|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 863
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|a Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer’s disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer’s disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson’s disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism.
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|a This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid’. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer’s disease-related dementia and Parkinson’s disease, as well as other less prevalent conditions like Huntington’s disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.
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|a Medicine.
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|a Pharmacy.
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|a Neurochemistry.
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|a Nutrition.
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|a Neurology.
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|a Biomedicine.
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|a Neurochemistry.
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| 650 |
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|a Nutrition.
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| 650 |
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|a Neurology.
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| 650 |
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|a Pharmacy.
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| 700 |
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|a Vassallo, Neville.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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| 776 |
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|i Printed edition:
|z 9783319183640
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| 830 |
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|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 863
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| 856 |
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|u http://dx.doi.org/10.1007/978-3-319-18365-7
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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