The Future of HIV-1 Therapeutics Resistance Is Futile? /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Torbett, Bruce E. (Επιμελητής έκδοσης), Goodsell, David S. (Επιμελητής έκδοσης), Richman, Douglas D. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Σειρά: Current Topics in Microbiology and Immunology, 389
• Θέματα: Medicine.; Drug resistance.; Virology.; Infectious diseases.; Biomedicine.; Drug Resistance.; Infectious Diseases.
• Φυσική περιγραφή: X, 254 p. online resource.
• ISBN: 9783319185187
• ISSN: 0070-217X ;

This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.