Computational Modelling of the Human Islet Amyloid Polypeptide

• Κύριος συγγραφέας: Skeby, Katrine Kirkeby (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Chemistry.; Chemoinformatics.; Bioorganic chemistry.; Medicinal chemistry.; Medicinal Chemistry.; Computer Applications in Chemistry.; Bioorganic Chemistry.

This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own...

Πίνακας περιεχομένων:

• Amyloid and Amyloid Fibrils
• Computational Theory
• Imaging Agent Binding to Amyloid Protofibrils
• Determining the Aggregation Prone Structure of hiAPP
• Effect of Terminal Capping on Aggregation of Peptide Fragments
• Coarse Grained Study of Amyloid Protofibril Aggregation
• Conclusion and Perspectives.