SH Domains Structure, Mechanisms and Applications /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Kurochkina, Natalya (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Subjects: Life sciences.; Proteins.; Cell biology.; Life Sciences.; Protein Science.; Protein Structure.; Protein-Ligand Interactions.; Cell Biology.

This book covers structure, function, and important roles of the SH domains, structure-function relationships, the versatile nature of their action, mechanisms of aggregation, specificity of interactions, impact of mutations on protein functional dysregulation, and cell signaling. Their involvement...

Table of Contents:

• SH3 Domains as Suitable Models to Study Amyloid Aggregation
• SH Domain Proteins in Plants: Roles in Signaling Transduction and Membrane Trafficking
• Versatility of SH3 Domains in the Cellular Machinery
• Structure-Function Relationship of Bacterial SH3 Domains
• Activation of PI3K by Thyroid Hormone Nuclear Receptors
• SH Domains’ Interaction with SliMs: Maximizing Adaptivity of Signaling Networks
• SH Domains and Epidermal Growth Factor Receptor
• SH2 Domain Structures and Interactions
• Cytoskeletal Signaling by Src Homology Domain-Containing Adaptor Proteins
• Structure and Function of Jak3- SH2 Domain
• Helical Assemblies and SH Domains.