The Adenosinergic System A Non-Dopaminergic Target in Parkinson’s Disease /

Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Morelli, Micaela (Επιμελητής έκδοσης), Simola, Nicola (Επιμελητής έκδοσης), Wardas, Jadwiga (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
Έκδοση:1st ed. 2015.
Σειρά:Current Topics in Neurotoxicity, 10
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Adenosine A2A receptors: localization and function
  • Allosteric Mechanisms in the adenosine A2A-dopamine D2 receptor heteromer
  • Adenosine A2A receptor antagonists in drug development
  • Adenosine A2A Receptors and Neurotrophic Factors: Relevance for Parkinson's Disease
  • Role of adenosine A2A receptors in the control of neuroinflammation – relevance for Parkinson’s disease
  • Purines in Parkinson's: Adenosine A2A receptors and urate as targets for neuroprotection
  • Adenosine A2A receptor antagonists as drugs for symptomatic control of Parkinson’s disease in preclinical studies
  • Dopamine/adenosine interactions related to tremor in animal models of Parkinsonism
  • Adenosine A2A receptor antagonists in L-DOPA-induced motor fluctuations
  • Adenosine A2A receptor-mediated control of non-motor functions in Parkinson’s disease
  • Imaging Studies with A2A Receptor Antagonists
  • Caffeine and neuroprotection in Parkinson's disease
  • The story of istradefylline – the first approved A2A antagonist for the treatment of Parkinson’s disease
  • Adenosinergic Receptor Antagonists: Clinical Experience in Parkinson's Disease
  • Adenosinergic regulation of sleep-wake behavior in the basal ganglia.