Chromosomal Instability in Cancer Cells

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ghadimi, B. Michael (Editor), Ried, Thomas (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Series: Recent Results in Cancer Research, 200
• Subjects: Medicine.; Cancer research.; Human genetics.; Oncology.; Medicine & Public Health.; Cancer Research.; Human Genetics.

This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in...

Table of Contents:

• DNA Repair and Chromosomal Translocations
• CINcere modelling: What have mouse models for chromosome instability taught us?
• Telomere Dysfunction, Chromosomal Instability and Cancer
• Genetic Instability and Disease Prognostication
• Causes of Chromosomal Instability
• Patterns of Chromosomal Aberrations in Solid Tumors
• Yeast as Models of Mitotic Fidelity
• The diverse effects of complex chromosome rearrangements and chromothripsis in cancer development
• Consequences of aneuploidy in cancer: transcriptome and beyond.