Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Hsu, Ellen (Επιμελητής έκδοσης), Du Pasquier, Louis (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Έκδοση: 1st ed. 2015.
• Σειρά: Results and Problems in Cell Differentiation, 57
• Θέματα: Medicine.; Immunology.; Parasitology.; Cell biology.; Evolutionary biology.; Biomedicine.; Evolutionary Biology.; Cell Biology.

This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens h...

Πίνακας περιεχομένων:

• Evolution of immunity and pathogens
• A host-pathogen interaction reduced to first principles: Antigenic variation in T. brucei
• Antigenic variation in Plasmodium falciparum
• Polymorphic mucin-like proteins in Schistosoma mansoni, a variable antigen and a key component of the compatibility between the schistosome and its snail host
• Fibrinogen-related proteins (FREP) in mollusks
• Somatic and germline diversification of a putative immunoreceptor within one phylum: Dscam in arthropods
• An immune effector system in the Protochordate gut sheds light on fundamental aspects of vertebrate immunity
• Variable lymphocyte receptors: a current view
• Antibody repertoire in fish
• Unique features of fish immune repertoires: particularities of the adaptive immunity within the largest group of vertebrates
• The evolution and structure of atypical T cell receptors
• Diversification of the primary antibody repertoire by AID-mediated gene conversion
• Antibody isotype switching in vertebrates.