Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Babashah, Sadegh (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Έκδοση: 1st ed. 2015.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Drug resistance.; Molecular biology.; Oncology.; Biomedicine.; Cancer Research.; Drug Resistance.; Molecular Medicine.; Human Genetics.

The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understandi...

Πίνακας περιεχομένων:

• Preface
• I. The Biology of Cancer Stem Cells
• Cancer Stem Cells: A Quick Walk through the Concepts
• Cytokine Networks and Cancer Stem Cells
• Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression
• Non-coding RNAs in Cancer and Cancer Stem Cells. Self-renewal Pathways in Mammary Stem Cells and Carcinogenesis II. Cancer Stem Cells in Human Malignancies
• Breast Cancer Stem Cells
• Lung Cancer Stem Cells
• Colorectal Cancer Stem Cells
• Pancreatic Cancer Stem Cells
• Glioblastoma Cancer Stem Cells
• Head and Neck Cancer Stem
• Leukemic and Lymphoid Stem Cells
• Leukemic Stem Cells in Acute Lymphoblastic Leukemia
• III. Novel Approaches for Targeting Cancer Stem Cells
• Targeting Key Stemness-Related Pathways in Human Cancers
• Targeting Cancer Stem Cells and the Tumor Microenvironment
• Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance
• Cancer Stem Cells and Tumor Radioresistance
• Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies. Index.