Synthetic and Biophysical Studies on the Tridachiahydropyrone Family of Natural Products

• Main Author: Powell, Kimberley Jade (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Spectroscopy.; Organic chemistry.; Organic Chemistry.; Biological and Medical Physics, Biophysics.; Spectroscopy/Spectrometry.

This thesis addresses fundamental scientific questions such as: How are complex natural products synthesized in vivo? Can we replicate these conditions in a laboratory environment? What is the biological function of such secondary metabolites? What are the biological origins of chirality? These issu...

Table of Contents:

• Introduction
• Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors
• Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies
• Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones
• Summary and Conclusions
• Experimental
• Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.