RNA/DNA and Cancer

• Κύριος συγγραφέας: Sinkovics, Joseph G. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Έκδοση: 1st ed. 2016.
• Θέματα: Medicine.; Cancer research.; Immunology.; Oncology.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.

In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in...

Πίνακας περιεχομένων:

• Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING
• The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes
• The First Cells Ascend
• Eukaryotic Single Cells and the First Cell Communities Then and Now
• A Highly Effective Immune System Predating Adaptive Immunity
• Elements of Adaptive Immunity Self-Assemble
• The RNA/DNA Complex at Work
• YY Proteins
• Elusive Alleles
• The Long Trajectory of the IGF-like Receptor and Its Ligands
• Primordial Fused Genes Become Oncogenes and Encode Oncoproteins
• Performance in the Laboratory
• Inbuilt Errors not yet Corrected
• Errors or Inherent Attributes for the Sustenance of Unicellular Life
• Viral Genomic Insertions into the Host Cell’s Genome
• Viral and Cellular Proteins Interact
• Light Cast to Broken DNA, Its Repair, and Consequences
• Undisciplined Introns
• Elementary Epigenomics
• RNA/DNA: Bioengineers Supreme
• II THE ONCOGENOME
• Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable
• Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted
• A Condensed Compendium
• “Malignant Transformation”
• III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA
• Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways
• The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba)
• Astute Observers Withstand Derision
• “Making Cancer History” at M.D. Anderson Hospital
• SUMMARY
• Appendix 1
• Appendix 2
• Index. .